1·VEGF is essential for embryonic development, endochondral bone formation, female reproductive functions. Substantial evidence also implicates VEGF in tumor and intraocular angiogenesis.
VEGF也是胚胎发育、软骨内骨形成、女性生殖系统、以及肿瘤和眼球内血管新生所必需的。
2·To determine the role of epidermal growth factor receptor (EGFR) signaling in endochondral ossification.
目的：探讨表皮生长因子受体（EGFR）信号转导在软骨内骨化中的作用。