1·AIM: To investigate the characteristics of the antinociceptive effects of choline in central nervous system (CNS) in mice.
目的:研究胆碱中枢镇痛效应的药效学特征。
2·Pharmacological tests show that the two monoterpene compounds disclosed by the invention have good antinociceptive effect.
药理实验表明本发明公布的两个单萜化合物具有良好的镇痛效果。
3·Conclusion Inhibition of chronic morphine-induced spinal JNK activation may be one of the mechanisms underlying the blockage of morphine antinociceptive tolerance by agmatine.
结论抑制慢性吗啡注射所引起的脊髓jnk的激活可能是胍丁胺抗吗啡镇痛耐受的作用机制之一。