1·These organisms penetrate into snails, multiply, and develop into cercariae, the infective form for man.
这些毛蚴进体螺体,繁殖和发育对人类有传染性的尾蚴。
2·Objective: To find out the major antigenic molecules of radiation attenuated cercariae, and provide some useful candidate antigens for developing schistosomiasis vaccine.
目的:寻找照射致弱尾蚴中起免疫保护作用的抗原分子,为血吸虫病疫苗研究提供新的候选抗原。
3·The worm reduction rate after challenging with mainland strain cercariae in mice immunized with rSj26 was 26~32%, similar to that in mice immunized with 24-26 kDa antigen.
若以两种抗原加福氏佐剂分别免疫小鼠,以日本血吸虫大陆株尾蚴攻击感染,减虫率相似(26~32%),表明两种抗原存在一定程度的交叉免疫保护性。
4·The miracidia can infect Oncomelania snails and the cercariae enable Apodemus agrarius and mice to develop infection.
虫卵孵出的毛蚴能感染钉螺,逸出的尾蚴能再感染姬鼠和小白鼠。
5·CONCLUSION: Cellular immune response in the skin of the mice immunized with UV-attenuated cercariae might play an important role in the protective immunity against challenge infection.
结论:提示皮肤组织的细胞免疫反应在血吸虫减毒尾蚴免疫的宿主抗攻击感染保护性免疫中起重要作用。