1·The key step of the two routes is the reaction of nucleophilic substitution of aromatic amines and -bromo compounds. Generally the produce rate of this reaction is low and the reaction time is long.
两条路线中关键的一步反应是芳胺和溴代化合物的亲核取代反应，一般这步反应产率很低，并且需要较长的反应时间。
2·The mechanism of Hofmann rearrangement reaction and the effects of alkyl structure and nucleophilic reagent in medium on the reaction are discussed.
讨论了Hofmann重排反应的机理以及烃基的结构、介质中的亲核试剂对反应的影响，并介绍了此重排在有机合成中的应用。
3·Michael reaction is a typical nucleophilic addition reaction, is always an organic chemistry domain research hot spot.
迈克尔反应是一个典型的亲核加成反应，一直是有机化学领域的一个研究热点。
4·Moclobelide was synthesized from ethanolamine by nucleophilic substitution and Schotten-Baumann reaction, followed by condensation with an overall yield of 71.2%.
以乙醇胺为起始原料，经亲核取代、肖特一鲍曼反应和缩合反应制得吗氯贝胺，总收率可达71.2%。
5·Kinetics of the Nucleophilic Substitution of 3-amino-1, 2, 4-triazole with Picryl Chloride.
氨基- 1,2,4 -三唑与苦基氯的亲核取代反应动力学研究。