1·However, antibiotic resistance of H. pylori, especially to clarithromycin and metronidazole, strongly undermined the efficacy of eradication treatment.
然而,幽门螺旋杆菌的抗生素耐药性,尤其是对克拉霉素和甲硝唑的耐药性,强烈的影响了根除治疗的疗效。
2·Objective To observe the clinical effect and reliability of the clarithromycin therapy of NGU.
目的观察克拉霉素治疗非淋菌性尿道炎的临床疗效和安全性。
3·OBJECTIVE: To study the relative bioavailability and bioequivalence of domestic clarithromycin granule, capsule and imported tablet.
目的:研究国产克拉霉素颗粒剂和胶囊与进口片剂的生物利用度和生物等效性。
4·Clarithromycin was prepared from erythromycin a through oximation, protection, methylation and deprotection. The overall yield of clarithromycin was 40%.
红霉素碱经肟化、保护再经甲基化、脱保护得到克拉霉素,总收率达40 %以上。
5·Conclusion: the healing effect of amoxicillin, clarithromycin, omeprazole triple therapy for helicobacter pylori-positive ulcers were ideal and worthy of clinical applying.
结论:阿莫西林、克拉霉素、奥美拉唑三联疗法治疗幽门螺杆菌阳性溃疡效果理想,值得临床推广使用。