1·Conclusion We did not find the difference between the two CYP2C19 phenotypes in relation to the acid-suppressing effect of esomeprazole.
结论未观察到CYP2C19基因多态性对埃索美拉唑的抑酸效应的影响。
2·Methods 100 Chinese patients that taking long term esomeprazole magnesium were choosed and randomized into 3 groups, and 30 normal Chinese were choosed as the controls.
方法选取长期服用埃索美拉唑镁片患者100例，根据服用时间长短随机分为3组，另选30例胃镜检查正常者作为正常对照组。
3·Objective to observe the influence of proton pump inhibitor (PPI) esomeprazole on antiplatelet effect of clopidogrel.
目的观察质子泵抑制剂埃索美拉唑是否影响氯吡格雷的抗血小板聚集作用。
4·Esomeprazole is a new member of proton pump inhibitors (PPI) with strong suppressive effects on gastric acid secretion.
埃索美拉唑是新一代质子泵抑制剂成员，有较强的抑制胃酸分泌效应。
5·CONCLUSION: Clinicians should tighten monitoring on the application of esomeprazole to reduce the occurrence of esomeprazole-induced ADR.
结论：临床上应加强埃索美拉唑合理应用的监测，以减少不良反应的发生。