1·With this new set of tools, Luger and her colleagues did X-ray crystallographic and biophysical studies to see how methylation affects the structure of chromatin and nucleosomes.
利用这种新型工具,Luger和他的同事进行了X射线晶体学和生物物理学研究,来看甲基化怎样影响染色质和核小体结构。
2·Nucleosomes; Lung cancer; Chemotherapy; Prediction; Monitoring.
核小体;肺癌;化疗;预测;监测。
3·As the genetic blueprint of life, DNA must be deciphered or "read," even when densely packed into nucleosomes.
DNA作为生命的遗传蓝图,必须被解码或被“阅读”,甚至在被紧密“打包”放进核小体的时候也是如此。