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bisphosphonates

二膦酸盐

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二膦酸盐

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二膦酸盐

Bisphosphonates appear to be a current mainstay for the treatment and prevention of the skeletal-related morbidity in cancers.

双膦酸盐类药物似乎是目前主体的治疗和预防的骨骼有关的发病率在癌症。

Concomitant use of bisphosphonates and stating did not further reduce the risk.

同时使用双磷酸盐和他汀类未能进一步降低风险。

About 10% of patients with bone metastases eventually develop hypercalcemia, which can be treated with IV bisphosphonates (eg, pamidronate).

的骨转移病人最终会患高钙血症，它可以用二膦酸盐静脉治疗（如氨羟二磷酸二钠）。

We also review the pharmacologic properties of bisphosphonates and their possible role in the pathophysiology of osteonecrosis.

我们还审查药理性能的双膦酸盐及其可能的病理生理作用的骨坏死。

Bisphosphonates may modestly affect clinical disease activity in ankylosing spondylitis.

二磷酸盐可能对强直性脊柱炎的临床疾病有轻微影响。

The Mayo Clinic team provided recommendations for the myeloma patients for whom bisphosphonates are indicated.

梅奥诊所给二膦酸盐化合物已经明确的骨髓瘤患者提供建议。

Bisphosphonates are prescription medications that, like other drugs, have multiple possible side effects.

双磷酸盐类，像其他药物，有多种可能的副作用的处方药物。

Bisphosphonates, which inhibit osteoclasts, alleviate many of the devastating consequences of metastatic bone disease.

双膦酸盐类药物，抑制破骨细胞，减轻许多破坏性后果骨转移疾病。

A dental examination before patients begin therapy with intravenous bisphosphonates is advisable if possible.

建议在病人在开始静脉注射双磷酸盐之前进行牙科检查。

Bisphosphonates is recommended for patients with bone metastases which can reduce the incidence of bone-related events.

伴有肾癌骨转移患者，推荐应用双膦酸盐药物，以减少骨相关事件的发生。

Bisphosphonates have become an integral component of the management of cancer patients who are at risk for treatment-induced bone loss.

对于具有治疗导致的骨量减少风险的肿瘤患者来说，双磷酸盐已经成为治疗中非常重要的一类药物。

Bisphosphonates are effective inhibitors of bone remodeling.

二膦酸盐是有效抑制骨改建。

Some individuals have harmful side effects with long-term use of bisphosphonates, the current main class of osteoporosis treatment drugs.

有些患者长期使用双膦酸盐会产生有害的副作用，它是目前治疗骨质疏松症的主流药物。

Endoscopic examination suggested gastric mucosal damage by NSAID is more serious than that of bisphosphonates.

内视镜检查显示胃粘膜损伤的非甾体抗炎药是更为严重的双膦酸盐。

The remaining 6 percent diagnosed with osteonecrosis of the jaw took oral bisphosphonates.

其余6%被诊断为骨坏死的患者则是口服二膦酸盐。

When taken orally, bisphosphonates are poorly absorbed and have low bioavailability.

口服双磷酸盐的吸收率及生物利用度非常低。

Bisphosphonates can now be distinguished based on their molecular and cellular mechanisms of action.

二膦酸盐，现在可以根据他们的尊敬的分子和细胞的作用机制。

She picked the drugs because of studies in humans that suggest bisphosphonates may help prevent cancer from spreading to the bone.

她之所以选择这些药物是因为在人类研究中表明双磷酸盐可以帮助阻止癌症扩散到骨骼。

However, bisphosphonates may play a role in the development of osteonecrosis of the jaws.

然而，二膦酸盐可发挥作用，发展颌骨骨坏死。

Our current understanding is that bisphosphonates may also disrupt the metastatic process and reduce the development of bone lesions.

我们目前的理解是，二膦酸盐也可能破坏转移过程，并减少开发骨病变。

For the study, researchers recruited about 2, 000 patients from 23 countries who were not taking oral bisphosphonates.

为进行这一试验，研究者们从23个国家招募了近2,000名没有服用过双膦酸盐类药物的患者。

Bisphosphonates have a chemical structure similar to that of pyrophosphate, part of the mineral phase of bone;

双磷酸盐具有和焦磷酸盐相类似的化学结构，还这正是骨矿物质成分的一种；

Review: bisphosphonates reduce fractures, radiotherapy, and hypercalcaemia and increase time to a first skeletal related event

综述：二膦酸盐可减少骨折、放疗、高钙血症并延缓首次骨骼事件发生时间

Clinical efficacy of bisphosphonates in the treatment of postmenopausal osteoporosis

二膦酸盐类药物治疗妇女绝经后骨质疏松症的疗效观察

A Synthetic Method of the Bone Resorption Inhibitor Amino-bisphosphonates and Their Sodium Salts

骨吸收抑制剂氨基二膦酸类化合物及其钠盐的合成

Recent Advances in Research and Reasonable Application of Bisphosphonates

双膦酸盐类药物的研究进展与合理应用

Therapeutic mechanism of bisphosphonates for metastatic tumor of bone

二磷酸盐治疗转移性骨肿瘤的作用机制

Clinical trial of bisphosphonates in bone metastasis due to solid tumor

双膦酸盐类在实体肿瘤骨转移中的临床应用

Review of the research of bisphosphonates in the management of periodontitis

双磷酸盐类药物用于牙周炎治疗的研究进展

Effects of bisphosphonates in treatment of women with osteoporosis

双膦酸盐类药物治疗骨质疏松症

1·A number of medications are available to help slow bone loss and maintain bone mass, including bisphosphonates (Fosamax, Actonel, Boniva) and raloxifene (Evista).

许多药物治疗可以有助于减缓骨质流失和保持骨量，其中包括二膦酸盐(福善美、Actonel、Boniva)和雷洛昔芬(Evista)。

2·Prevention of vascular calcification with bisphosphonates without affecting bone mineralization: a new challenge?

不影响骨质矿化的二膦酸盐预防血管钙化的作用：新的挑战？

网络释义

双磷酸盐类

而双磷酸盐类（Bisphosphonates）的出现，成为治疗骨质疏松症及其他低骨质/高骨转化率（Low bone mass / High bone turno…

双磷酸盐类药物

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双膦酸盐类

双膦酸盐类(bisphosphonates)药物已发展成为最有效的骨吸收抑制剂。由于它能减少各种原因引起的骨吸收，因此被用来预防 …

二磷酸盐

二磷酸盐（bisphosphonates）自从30多年前被发现对于钙盐代谢的潜在作用以来，己成为临床上最重要、最成功的抗骨吸收药 …

双磷酸盐药物

双磷酸盐药物 (Bisphosphonates)可能是目前医师比较喜欢开的药物，原因是它的安全与方便。双磷酸盐药物上市已超过10年， …

更新时间：2025-02-22 13:49