1·Objective: To evaluate the effect of osteopontin as serum tumor marker on the diagnosis of pancreatic cancer.
目的：评价骨桥蛋白作为肿瘤血清标记物在胰腺癌诊断中的作用。
2·Osteopontin is a glycoprotein involved in inflammation, angiogenesis, and metastasis, and has been found in higher levels in cancer patients with metastatic disease.
骨桥蛋白是一种参与炎症、血管生成和转移的糖蛋白，研究发现其在发生癌症转移的病人中血中表达水平较高。
3·The researchers also found that osteopontin gene expression triggered the expression of profibrogenic genes.
研究者也发现骨桥蛋白基因的表达触发了纤维蛋白酶原基因的表达。
4·After analyzing the plasma levels of 80 known human cytokines, the investigators identified osteopontin as a necessary factor for recruitment of BMCs and subsequent tumor growth.
在分析了80种已知的人类细胞因子的血清中水平后，研究者们发现骨桥蛋白作为一种必需因子对BMC的聚集和以后的肿瘤生长具有重要作用。
5·Objective To investigate the expression of osteopontin (OPN) in non-small cell lung cancer (NSCLC).
目的研究骨桥蛋白(OPN)在非小细胞肺癌(NSCLC)中的表达。